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Organic Acids Test (OAT) + NAD

Feeling tired, foggy or off despite “normal” blood work? The Organic Acids Test uncovers hidden nutrient, gut, and metabolic imbalances that could explain your symptoms.
£305
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The Organic Acids Test: A Deeper Look at Fatigue, Brain Fog & Gut Health

The Organic Acids Test is a functional health assessment that evaluates more than 130 organic acid markers from a single urine specimen. These markers are by-products of critical metabolic pathways, and they reflect real-time information about how your body is working behind the scenes - from energy production and gut health to brain chemistry, detoxification, nutrient status, and environmental chemical exposure.

As opposed to regular blood tests, which look at fixed levels of nutrients or hormone status, the Organic Acids Test looks at dynamic processes like how your cells are using nutrients, what they lack, and whether key systems like detox or energy production are in stress.

It’s particularly useful for people experiencing persistent symptoms that don’t show up clearly in standard lab work. Think of it as a behind-the-scenes look at how your body’s systems are actually functioning.

You can find out more information in our blog.

What's included

Your cells turn food into energy through a series of chemical steps inside the mitochondria, and this area measures the by-products of those steps to see how smoothly the process is running. Isolated findings here are common and often shift with diet or recent activity - the pattern across markers matters more than any single result.

When your body uses fat as fuel, it produces certain metabolites. High levels of Adipic Acid, Suberic Acid, or Ethylmalonic Acid may point to issues with fat metabolism, which is often due to carnitine or riboflavin (B2) deficiencies.

Your B-vitamins contribute to almost every metabolic process. These markers help detect where additional B1, B2, B3, B5, B6, or biotin may be needed to aid with symptoms like fatigue or hormonal imbalance.

The citric acid (Krebs) cycle is the method by which your body turns food into cellular energy (ATP). Issues here typically cause low energy, brain fog, and intolerance to exercise.

After your body uses brain chemicals like dopamine, serotonin, and adrenaline, it breaks them down into smaller by-products that pass out in urine, which this area measures as an indirect read on messenger activity. These markers are influenced by diet, sleep, stress, caffeine and medications, so a single reading is rarely diagnostic on its own. This area also calculates key ratios between these markers, which can reveal whether inflammation is diverting resources away from brain chemical production.

This area looks at how well your body is handling everyday cellular wear-and-tear and clearing the substances your liver needs to process - medications, hormones, alcohol, and the by-products of your own metabolism. Temporary elevations are common after intense exercise, illness, or high alcohol intake, and are usually not concerning in isolation. It also includes a direct inflammation marker and an antioxidant status marker, giving a broader picture of your body’s inflammatory and protective balance.

This area screens for chemical traces that your body leaves behind after processing common environmental substances - solvents found in paints, fuels, and adhesives; plasticisers in food packaging and plastic products; preservatives in cosmetics and personal care products; and compounds from vehicle exhaust and cigarette smoke. A raised reading doesn’t necessarily mean you’re being harmed - it’s a prompt to think about where the exposure might be coming from and whether it can be reduced.

This area looks at chemicals produced by the trillions of microbes living in your gut, giving a rough read on which microbial groups are more or less active than usual. It won't tell you exactly which species are present, but it can flag patterns worth a closer look with your clinician.

Oxalates are naturally occurring substances in foods like spinach and almonds, however, when your gut flora is out of balance, excess oxalates are absorbed, which can cause joint pain, urinary discomfort, skin rashes, fatigue, or brain fog.

This area combines two different views of your nutrient status: "functional" markers that rise when your body is working harder to use a vitamin, and direct measurements of vitamins passing through in urine. Together they give a rough indication of which nutrients may be in higher demand, though a blood test is still the gold standard for confirming any specific deficiency.

NAD does not occur directly in food. However, the building blocks for NAD, which are vitamins and amino acids, can be found in various foods. These building blocks are then absorbed by the body and converted into NAD through metabolic processes.

Age and sex-related NAD decline refers to the reduction in NAD+ levels as humans age, with differences observed between males and females. Studies show that NAD+ concentration decreases with age, though the exact rate of decline isn't always calculated. Women generally have higher NAD+ levels compared to men, but this difference lessens over time. This topic is emerging in research, but offers potential for understanding ageing and developing new treatments. Ranges are based on the following study: https://pmc.ncbi.nlm.nih.gov/articles/PMC8979162/

Test instructions

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You’ll receive your urine & blood spot card tests kit in the mail, along with logistics for your sample collection.

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Follow the test preparation instructions provided noting any foods, drinks, medications or otherwise to avoid within specific timeframes of completing the test

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Mail your sample back to the lab using the prepaid envelope and packaging.

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Results for this test available in 16-20 business days weeks will be published in your online dashboard.

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